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KMID : 0043320070300060695
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Archives of Pharmacal Research
2007 Volume.30 No. 6 p.695 ~ p.700
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Stereoselective Synthesis of (E)- and (Z)-Enol Ethers from β-Amino Aldehydes
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In Jin-Kyung
Lee Mi-Sung
Lee Min-Woo
Kwak Jae-Hwan
Lee Hee-Soon
Hong Jin-Tae
Chung Yong-Seog
Choi Yong-seok
Jung Jae-Kyeong
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Abstract
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Stereocontrolled methods for the direct and divergent synthesis of the silylenol ethers possessing amino group from β-amino aldehydes have been achieved. These enol ethers with the defined olefin geometry could be key building blocks for the synthesis of the medicinally important compounds.
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KEYWORD
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Enol ether, β-Amino aldehyde, Building block
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